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Heterochronic parabiosis: historical perspective and methodological considerations for studies of aging and longevity

14 Mar 2013

Abstract excerpt

Pairing two animals in parabiosis to test for systemic or circulatory factors from one animal affecting the other animal has been used in scientific studies for at least 150 years. These studies have led to advances in fields as diverse as endocrinology, immunology, and oncology. A variation on the technique, heterochronic parabiosis, whereby two animals of different ages are joined to test for systemic...

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PMID: 23489470
DOI: 10.1111/acel.12065

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