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Heterochronic parabiosis for the study of the effects of aging on stem cells and their niches

11 Jun 2012

Abstract excerpt

Aging is unmistakable and undeniable in mammals. Interestingly, mice develop cataracts, muscle atrophy, osteoporosis, obesity, diabetes and cognitive deficits after just 2-3 postnatal years, while it takes seven or more decades for the same age-specific phenotypes to develop in humans. Thus, chronological age corresponds differently with biological age in metazoan species and although many theories exist, we do...

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PMID: 22617385
DOI: 10.4161/cc.20437

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