Article
Association of interleukin 2 (IL-2), interleukin 6 (IL-6), and TNF-alpha (TNFα) gene polymorphisms with paranoid schizophrenia in a Polish population.
The Journal of neuropsychiatry and clinical neurosciences - 1 Jan 2013
Paul-Samojedny Monika, Owczarek Aleksander, Kowalczyk Małgorzata, Suchanek Renata, Palacz Marta, Kucia Krzysztof, Fila-Daniłow Anna, Borkowska Paulina, Kowalski Jan
Abstract excerpt
Numerous reports have brought attention to the potential role of cytokines in schizophrenia. The aim of the study was to determine whether polymorphisms of IL-2, IL-6, and TNFα genes are risk factors for development of paranoid schizophrenia in a Polish population. Promoter polymorphisms of IL-6 (rs1800795), TNFα (rs1800629), and IL-2 (rs2069762) genes in patients (N=115) and controls (N=135) were genotyped by...
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