Article
Association of APOA1 and APOA5 polymorphisms and haplotypes with lipid parameters in a Brazilian elderly cohort.
Genetics and molecular research : GMR - 28 Feb 2013
Furuya T K, Chen E S, Ota V K, Mazzotti D R, Ramos L R, Cendoroglo M S, Araujo L Q, Burbano R R, Smith M A C
Abstract excerpt
Apolipoproteins have an important role in lipid metabolism and transport. Polymorphisms in the APOA1/C3/A4/A5 gene cluster have been associated with lipid alterations and cardiovascular diseases. We investigated APOA1 XmnI, APOA5 S19W, and APOA5 -1131T>C polymorphisms in 377 individuals from a cohort of a longitudinal Brazilian elderly study. Allele frequencies, genotype distribution, and association with major...
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