Article
APOA1/A5 variants and haplotypes as a risk factor for obesity and better lipid profiles in a Brazilian Elderly Cohort.
Lipids - 1 Jun 2010
Chen Elizabeth Suchi, Furuya Tatiane Katsue, Mazzotti Diego Robles, Ota Vanessa Kiyomi, Cendoroglo Maysa Seabra, Ramos Luiz Roberto, Araujo Lara Quirino, Burbano Rommel Rodriguez, de Arruda Cardoso Smith Marília
Abstract excerpt
Genetic variations in the APOA1/C3/A4/A5 gene cluster have been studied and proposed to be the leading key for susceptibility to cardiovascular diseases and age-associated disorders. We aimed to investigate the associations of rs12721026 (APOA1) and rs1729408 (APOA5) polymorphisms and their haplotypes with some age-related diseases, as well as with lipids and proteins serum levels in a cohort from a Brazilian...
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