Article
APOA5 polymorphisms associated with lipid metabolism in Brazilian children and adolescents.
Genetics and molecular research : GMR - 31 Mar 2016
De França E, Silva D S B S, Silva T F C, Dornelles C L, Alves J G, Alho C S
Abstract excerpt
Single nucleotide polymorphisms in the APOA5 gene have been studied for their association with metabolic syndrome. Thus, elucidating the effect of the mechanism involved in APOA5 gene polymorphisms on lipid metabolism is of great importance. In this study we aimed to determine the allelic and genotypic frequencies of -1131T>C, Ser19Trp, and intergenic APOA4/A5 and to evaluate the association between these...
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