Article
CYP1A1 MspI polymorphism is associated with prostate cancer susceptibility: evidence from a meta-analysis.
Molecular biology reports - 1 May 2013
Ding Gang, Xu Weiguo, Liu Hedai, Zhang Ming, Huang Qian, Liao Zhijun
Abstract excerpt
Cytochrome P450 1A1 (CYP1A1), an important phase I xenobiotic metabolizing enzyme, is responsible for metabolizing numerous carcinogens, particularly polycyclic aromatic hydrocarbons. The genetic polymorphism of CYP1A1 at the site of MspI (CYP1A1 MspI) has been implicated in prostate cancer risk, but the results of individual studies remain conflicting and inconclusive. The aim of this meta-analysis was to...
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