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Article

Genetic modifiers of cancer risk in Lynch syndrome: a review.

Familial cancer - 1 Jun 2013

Talseth-Palmer Bente A, Wijnen Juul T, Grice Desma M, Scott Rodney J

Abstract excerpt

The report by Aldred Scott Warthin in 1913 of a cancer family history and expanded on by Henry T. Lynch demonstrated one of the most enduring traits observed in patients with Lynch syndrome. The recognition of a variety of malignancies occurring at differing ages within a single family suggested the role of genetic variance on disease expression in an autosomal dominantly inherited genetic condition. With the...

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Identifiers

PMID: 23471748
DOI: 10.1007/s10689-013-9614-2
PMCID: PMC3717148

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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