Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mismatch repair defects and Lynch syndrome: The role of the basic scientist in the battle against cancer.

DNA repair - 1 Feb 2016

Heinen Christopher D

Abstract excerpt

We have currently entered a genomic era of cancer research which may soon lead to a genomic era of cancer treatment. Patient DNA sequencing information may lead to a personalized approach to managing an individual's cancer as well as future cancer risk. The success of this approach, however, begins not necessarily in the clinician's office, but rather at the laboratory bench of the basic scientist. The basic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Colorectal Cancer Screening and Detection
Share to Colorectal Cancer Treatments and Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Colorectal Neoplasms, Hereditary Nonpolyposis

Share to DNA Mismatch Repair

Share to Genes, Neoplasm

Share to Genetic factors in colorectal cancer

Share to Mutation

Source

Open in PubMed Open full text

Identifiers

PMID: 26710976
DOI: 10.1016/j.dnarep.2015.11.025
PMCID: PMC4740212

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mismatch repair defects and Lynch syndrome: The role of the basic scientist in the battle against cancer.PMID 26710976Read ↗

Recent Advances in Lynch Syndrome: Diagnosis, Treatment, and Cancer PreventionSemantic proximity Read ↗

The mechanism of mismatch repair and the functional analysis of mismatch repair defects in Lynch syndromeSemantic proximity Read ↗

The Mystery of Mismatch Repair Deficiency: Lynch or Lynch-like?Semantic proximity Read ↗

New Insights into Lynch Syndrome: A Narrative Review.Semantic proximity Read ↗

Recent advances in understanding Lynch syndromeSemantic proximity Read ↗

Genetic and genomic basis of the mismatch repair system involved in Lynch syndromeSemantic proximity Read ↗

Genetics, diagnosis and treatment of Lynch syndrome: Old lessons and current challenges (Review)Semantic proximity Read ↗

DNA mismatch repair proteins: scientific update and practical guide.Semantic proximity Read ↗

Lynch syndrome: the patients' perspective.Semantic proximity Read ↗

Updates in gynecologic care for individuals with lynch syndromeSemantic proximity Read ↗

Review article: Lynch Syndrome—a mechanistic and clinical management updateSemantic proximity Read ↗

Mismatch repair gene deficiency and genetic anticipation in Lynch syndrome: myth or reality?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.