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Article

Mitochondrial toxicity studied with the PBMC of children from the Chinese national pediatric highly active antiretroviral therapy cohort.

PloS one - 1 Jan 2013

Liu Kai, Sun Yu, Liu Daojie, Yin Jiming, Qiao Luxin, Shi Ying, Dong Yaowu, Li Ning, Zhang Fujie, Chen Dexi

Abstract excerpt

As the backbone of highly active antiretroviral therapy (HAART), nucleoside reverse transcriptase inhibitors (NRTIs) have effectively improved outcomes for HIV-infected patients. However, long-term treatment with NRTIs can cause a series of pathologies associated with mitochondrial toxicity. To d...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23468942
DOI: 10.1371/journal.pone.0057223
PMCID: PMC3584138

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23468942-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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