Article
XRCC1 Arg399Gln polymorphism and risk for cervical cancer development in Argentine women.
European journal of gynaecological oncology - 1 Jan 2011
Barbisan G, Pérez L O, Difranza L, Fernández C J, Ciancio N E, Golijow C D
Abstract excerpt
BACKGROUND: XRCC1 (X-ray repair cross-complementing group 1) plays a central role in the DNA base excision repair mechanism. Single nucleotide polymorphisms (SNPs) in the XRCC1 gene are thought to modulate DNA repair capacity and have been linked to cancer risk in several studies. MATERIALS AND METHODS: We conducted a case-control study comprising 217 cervical samples, including 103 cervical carcinomas and 114...
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