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Article

Analysis of FOXO1 mutations in diffuse large B-cell lymphoma.

Blood - 2 May 2013

Trinh Diane L, Scott David W, Morin Ryan D, Mendez-Lago Maria, An Jianghong, Jones Steven J M, Mungall Andrew J, Zhao Yongjun, Schein Jacqueline, Steidl Christian, Connors Joseph M, Gascoyne Randy D, Marra Marco A

Abstract excerpt

Diffuse large B-cell lymphoma (DLBCL) accounts for 30% to 40% of newly diagnosed lymphomas and has an overall cure rate of approximately 60%. Previously, we observed FOXO1 mutations in non-Hodgkin lymphoma patient samples. To explore the effects of FOXO1 mutations, we assessed FOXO1 status in 279 DLBCL patient samples and 22 DLBCL-derived cell lines. FOXO1 mutations were found in 8.6% (24/279) of DLBCL cases:...

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Share to Cell Line, Tumor
Share to DNA Mutational Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Forkhead Box Protein O1

Share to Forkhead Transcription Factors

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Share to Lymphoma, Large B-Cell, Diffuse

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Source

Open in PubMed Open full text

Identifiers

PMID: 23460611
DOI: 10.1182/blood-2013-01-479865
PMCID: PMC3643765

Genes

FOXO1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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