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Article

Spinal muscular atrophy: a delayed development hypothesis

27 Apr 2005

Abstract excerpt

Spinal muscular atrophy is an inherited neuromuscular disorder. The gene responsible for the disease has been identified and named the SMN gene. This review is prompted by recent advances in understanding cellular function of the SMN gene and its gene product and by the increasing evidence that maturation of all parts of the neuromuscular system is delayed in spinal muscular atrophy patients. We suggest that the...

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PMID: 15858401
DOI: 10.1097/00001756-200505120-00001

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