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Advances in Biophotonics Detection of Field Carcinogenesis for Colon Cancer Risk Stratification

1 Jan 2013

Abstract excerpt

The process of neoplastic transformation of the colon involves a progression through hyperproliferative epithelium through the aberrant crypt foci→small adenoma→large adenoma→invasive cancer→metastatic disease. These are orchestrated by sequential genetic and epigenetic events which provide the underpinnings of cellular alterations such as early induction in proliferation/suppression of apoptosis, along with the...

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PMID: 23459690
DOI: 10.7150/jca.5838

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