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Article

Inverse correlation of soluble programmed cell death-1 ligand-1 (sPD-L1) with eosinophil count and clinical severity in allergic rhinitis patients.

Allergology international : official journal of the Japanese Society of Allergology - 1 Apr 2017

Nasiri Kalmarzi Rasoul, Fattahi Nima, Kaviani Zeinab, Ataee Pedram, Mansouri Majid, Moradi Ghobad, Yousefzade Alireza, Abbassi Javid Morad

Abstract excerpt

BACKGROUND: T-cell response outcome is determined by co-stimulatory/inhibitory signals. Programmed cell death-1 ligand-1 (PD-L1) is a member of these co-signaling molecules with known soluble form in human serum. Soluble PD-L1 (sPD-L1) is also recognized in patients with some types of malignancy or autoimmune disorders, though there are few studies on sPD-L1 roles in allergic diseases. The purpose of this survey...

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PMID: 27617656
DOI: 10.1016/j.alit.2016.08.008

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