Article
Association of polymorphisms in the Chr18q11.2 locus with tuberculosis in Chinese population.
Human genetics - 1 Jun 2013
Wang Xingyan, Tang Nelson Leung-Sang, Leung Chi Chiu, Kam Kai Man, Yew Wing Wai, Tam Cheuk Ming, Chan Chiu Yeung
Abstract excerpt
A GWAS study has reported that two single nucleotide polymorphisms (SNPs) were associated with predisposition to tuberculosis (TB) in African populations. These two loci represented the long-waited GWAS hits for TB susceptibility. To determine whether these two SNPs are associated with TB in Chinese population, we attempted an replication in a cohort of over one thousand Chinese TB patients and 1,280 healthy...
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