Article
Lack of association between polymorphisms from genome-wide association studies and tuberculosis in the Chinese population.
Scandinavian journal of infectious diseases - 1 Apr 2013
Ji Lin-Dan, Chai Peng-Fei, Zhou Bi-Bo, Tang Nelson L S, Xing Wen-Hua, Yuan Fang, Fei Li-Juan, Zhang Li-Na, Xu Jin
Abstract excerpt
Genome-wide association studies (GWAS) have identified rs4331426 and rs2057178 as being associated with tuberculosis (TB) in African populations. Both are common single nucleotide polymorphisms (SNPs) in Africans, but they are much rarer in Eurasian populations. In order to corroborate these results, we carried out a case-control study in the Chinese population; these 2 SNPs were genotyped in 600 pulmonary TB...
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