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Article

Hydrocarbons (jet fuel JP-8) induce epigenetic transgenerational inheritance of obesity, reproductive disease and sperm epimutations.

Reproductive toxicology (Elmsford, N.Y.) - 1 Apr 2013

Tracey Rebecca, Manikkam Mohan, Guerrero-Bosagna Carlos, Skinner Michael K

Abstract excerpt

Environmental compounds have been shown to promote epigenetic transgenerational inheritance of disease. The current study was designed to determine if a hydrocarbon mixture involving jet fuel (JP-8) promotes epigenetic transgenerational inheritance of disease. Gestating F0 generation female rats were transiently exposed during the fetal gonadal development period. The direct exposure F1 generation had an...

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Identifiers

PMID: 23453003
DOI: 10.1016/j.reprotox.2012.11.011
PMCID: PMC3587983

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