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Article

Ancestral dichlorodiphenyltrichloroethane (DDT) exposure promotes epigenetic transgenerational inheritance of obesity.

BMC medicine - 23 Oct 2013

Skinner Michael K, Manikkam Mohan, Tracey Rebecca, Guerrero-Bosagna Carlos, Haque Muksitul, Nilsson Eric E

Abstract excerpt

BACKGROUND: Ancestral environmental exposures to a variety of environmental factors and toxicants have been shown to promote the epigenetic transgenerational inheritance of adult onset disease. The present work examined the potential transgenerational actions of the insecticide dichlorodiphenyltrichloroethane (DDT) on obesity and associated disease. METHODS: Outbred gestating female rats were transiently exposed...

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Source

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Identifiers

PMID: 24228800
DOI: 10.1186/1741-7015-11-228
PMCID: PMC3853586

Genes

DDT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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