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Article

Plastics derived endocrine disruptors (BPA, DEHP and DBP) induce epigenetic transgenerational inheritance of obesity, reproductive disease and sperm epimutations.

PloS one - 1 Jan 2013

Manikkam Mohan, Tracey Rebecca, Guerrero-Bosagna Carlos, Skinner Michael K

Abstract excerpt

Environmental compounds are known to promote epigenetic transgenerational inheritance of adult onset disease in subsequent generations (F1-F3) following ancestral exposure during fetal gonadal sex determination. The current study was designed to determine if a mixture of plastic derived endocrine disruptor compounds bisphenol-A (BPA), bis(2-ethylhexyl)phthalate (DEHP) and dibutyl phthalate (DBP) at two different...

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Share to Endocrine Disruptors
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23359474
DOI: 10.1371/journal.pone.0055387
PMCID: PMC3554682

Genes

DBP

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