Article
[Association between mutations of SCN9A gene and pain related to Parkinsonism].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Feb 2013
Zhang Li-mei, Chen Yong-qian, Li Wan-jun, Sun Wei, Huang Yue, Zou Hai-qiang
Abstract excerpt
OBJECTIVE: To screening mutations of exons 15, 18 and 26 of sodium channel Nav1.7 (SCN9A) gene, and to assess its association with pain related to Parkinsonism. METHODS: Respectively, 101 patients with primary Parkinson's disease (PD) and 104 similar-aged volunteers without PD were recruited from March, 2008 to January, 2011. Mutations of above 3 exons in SCN9A gene was detected with PCR and direct sequencing....
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