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Article

Higher bone marrow LGALS3 expression is an independent unfavorable prognostic factor for overall survival in patients with acute myeloid leukemia.

Blood - 18 Apr 2013

Cheng Chieh-Lung, Hou Hsin-An, Lee Ming-Cheng, Liu Chieh-Yu, Jhuang Jie-Yang, Lai Yan-Jun, Lin Chung-Wu, Chen Huan-Yuan, Liu Fu-Tong, Chou Wen-Chien, Chen Chien-Yuan, Tang Jih-Luh, Yao Ming, Huang Shang-Yi, Ko Bor-Sheng, Wu Shang-Ju, Tsay Woei, Tien Hwei-Fang

Abstract excerpt

Alterations of galectin-3 expression are often seen in cancers and may contribute to tumorigenesis, cancer progression, and metastasis. The studies concerning clinical implications of galectin-3 expression in patients with acute myeloid leukemia (AML) are scarce. We investigated the expression of LGALS3, the gene encoding galectin-3, in the bone marrow (BM) mononuclear cells from an original cohort comprising 280...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23449638
DOI: 10.1182/blood-2012-07-443762

Genes

LGALS3
FLT3
PTPN11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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