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Mediators of low-grade chronic inflammation in polycystic ovary syndrome (PCOS).

Current pharmaceutical design - 1 Jan 2013

Ojeda-Ojeda Miriam, Murri Mora, Insenser María, Escobar-Morreale Héctor F

Abstract excerpt

Chronic low-grade subclinical inflammation has been increasingly recognized as an interposer in the endocrine, metabolic and reproductive disturbances that characterize the polycystic ovary syndrome (PCOS). Abdominal adiposity and obesity are often present in PCOS. Mounting evidence indicates that adipose tissue is involved in innate and adaptive immune responses. Continuous release of inflammatory mediators such...

Topics

Abdominal Fat
Adiposity
Cardiovascular Diseases
Chronic Disease
Female
Genetic Variation
Humans
Inflammation
Inflammation Mediators
Insulin Resistance
Obesity

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Polycystic Ovary Syndrome

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PMID: 23448487
DOI: 10.2174/1381612811319320012

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