Article
Mediators of chronic inflammation in polycystic ovarian syndrome.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology - 1 Dec 2012
Deligeoroglou E, Vrachnis N, Athanasopoulos N, Iliodromiti Z, Sifakis S, Iliodromiti S, Siristatidis C, Creatsas G
Abstract excerpt
Polycystic ovarian syndrome (PCOS) is an endocrine disorder affecting 5-10% of reproductive-age women. Hyperandrogenemia, which characterizes the syndrome, stimulates the maturation of adipocytes and favors central obesity. The linking hub between obesity and other metabolic manifestations of the syndrome seems to be chronic low-grade inflammation. We discuss the most reliable current data regarding the role of...
Topics
- Adipose Tissue
- Blood Coagulation Disorders
- Cell Adhesion Molecules
- Endothelium, Vascular
- Female
- Genetic Predisposition to Disease
- Humans
- Inflammation Mediators
- Polycystic Ovary Syndrome
- Polymorphism, Genetic
