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Article

The role of chronic inflammation and Leu55Met PON1 polymorphism in the pathogenesis of polycystic ovary syndrome.

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology - 1 Sept 2010

Lenarcik Agnieszka, Bidzińska-Speichert Bozena, Tworowska-Bardzińska Urszula

Abstract excerpt

INTRODUCTION: Polycystic ovary syndrome (PCOS) is an endocrine disorder with a complex pathogenesis in which hormonal disturbances, metabolic disorders and chronic inflammation have been considered. Relationships among the paraoxonase 1 (PON1) gene, hyperandrogenism and insulin resistance in women with PCOS have been reported. AIM: The aim of this study was to evaluate patients with PCOS for the existence of...

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Identifiers

PMID: 20334584
DOI: 10.3109/09513591003686387

Genes

PON1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The role of chronic inflammation and Leu55Met PON1 polymorphism in the pathogenesis of polycystic ovary syndrome.PMID 20334584Read ↗

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Mediators of chronic inflammation in polycystic ovarian syndrome.Semantic proximity Read ↗

PON1 polymorphisms are associated with polycystic ovary syndrome susceptibility, related traits, and PON1 activity in Indian women with the syndrome.Semantic proximity Read ↗

Mitochondrial Dysfunction and Chronic Inflammation in Polycystic Ovary Syndrome.Semantic proximity Read ↗

The association between paraoxonase 1 gene polymorphisms and polycystic ovarian syndrome.Semantic proximity Read ↗

Genetic Variability in Antioxidative and Inflammatory Pathways Modifies the Risk for PCOS and Influences Metabolic Profile of the SyndromeSemantic proximity Read ↗

Association of PON1 gene polymorphisms with polycystic ovarian syndrome risk: a meta-analysis of case-control studies.Semantic proximity Read ↗

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Association of Paraoxonase 1 Gene Polymorphisms and Polycystic Ovarian Syndrome Susceptibility: A Systematic Review and Meta-Analysis.Semantic proximity Read ↗

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