Article
Recurrent pregnancy loss, plasminogen activator inhibitor-1 (-675) 4G/5G polymorphism and antiphospholipid antibodies in Czech women.
American journal of reproductive immunology (New York, N.Y. : 1989) - 1 Jul 2013
Subrt Ivan, Ulcova-Gallova Zdenka, Cerna Monika, Hejnalova Marketa, Slovanova Jitka, Bibkova Katarina, Micanova Zdenka
Abstract excerpt
PROBLEM: This study compares the frequencies of plasminogen activator inhibitor-1 (-675) 4G/5G polymorphism and its relationship with eight antiphospholipid antibodies (aPLs) in serum of 157 patients with repeated pregnancy loss (RPL). METHOD OF STUDY: PAI-1 (-675) 4G/5G polymorphism was determined using standard PCR-RFLP method. Enzyme-linked immunosorbent assay was used for the detection of aPLs against...
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