Article
[Implication of PAI-1 4G/5G polymorphism in recurrent implantation failure after IVF].
Akusherstvo i ginekologiia - 1 Jan 2014
Ivanov P, Ivanov P, Gacheva Sv, Konova E, Komsa-Penkova R
Abstract excerpt
During implantation, an accurate balance of coagulation, fibrin deposition and fibrinolysis is mandatory for trophoblastic invasion. Inhibition of fibrinolysis after increased activity of plasminogen activator inhibitors such as PAI-1 could impair properdeep trophoblastic invasion. This study investigated correlation between increased PAI-1 levels due to gene polymorphism (PL) 4G/5G and recurrent implantation...
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