Article
The effect of methylenetetrahydrofolate reductase polymorphism C677T on cervical cancer in Korean women.
Gynecologic oncology - 1 Dec 2004
Sull Jae Woong, Jee Sun Ha, Yi Sangwook, Lee Jong Eun, Park Jong Sup, Kim Sook, Ohrr Heechoul
Abstract excerpt
OBJECTIVES: Methylenetetrahydrofolate reductase (MTHFR) gene is associated with DNA hypomethylation, an established hallmark of human cancer cells. The aim of this study was to examine the effect of MTHFR polymorphism C677T on cervical carcinogenesis in the context of other environmental factors, such as smoking, parity, and age at the first intercourse. METHODS: The study subjects were patients who were...
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