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Article

Interleukin-6 polymorphisms, Helicobacter pylori infection in adult Brazilian patients with chronic gastritis and gastric adenocarcinoma.

Archives of medical research - 1 Jul 2007

Gatti Luciano Lobo, Burbano Rommel Rodríguez, Zambaldi-Tunes Maurício, de-Lábio Roger Willian, de Assumpção Paulo Pimentel, de Arruda Cardoso-Smith Marília, Marques-Payão Spencer Luiz

Abstract excerpt

BACKGROUND: The discovery of Helicobacter pylori offered the etiologic agent of the initiating event of the inflammatory cascade. It has been confirmed that the development of gastric cancer spans over several decades sequentially starting with the acquisition of H. pylori infection and the development of chronic gastritis. The IL-6 gene (Il-6), inflammatory cytokine and the single-nucleotide polymorphisms (SNPs)...

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PMID: 17560462
DOI: 10.1016/j.arcmed.2006.12.011

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