Article
OXA-235, a novel class D β-lactamase involved in resistance to carbapenems in Acinetobacter baumannii.
Antimicrobial agents and chemotherapy - 1 May 2013
Higgins Paul G, Pérez-Llarena Francisco J, Zander Esther, Fernández Ana, Bou Germán, Seifert Harald
Abstract excerpt
We investigated the mechanism of carbapenem resistance in 10 Acinetobacter baumannii strains isolated from the United States and Mexico between 2005 and 2009. The detection of known metallo-β-lactamase or carbapenem-hydrolyzing oxacillinase (OXA) genes by PCR was negative. The presence of plasmid-encoded carbapenem resistance genes was investigated by transformation of A. baumannii ATCC 17978. Shotgun cloning...
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