Article
The role of the genetic elements bla oxa and IS Aba 1 in the Acinetobacter calcoaceticus-Acinetobacter baumannii complex in carbapenem resistance in the hospital setting.
Revista da Sociedade Brasileira de Medicina Tropical - 1 Jan 2000
Kobs Vanessa Cristine, Ferreira Jéssica Augustini, Bobrowicz Thaís Alexandra, Ferreira Leslie Ecker, Deglmann Roseneide Campos, Westphal Glauco Adrieno, França Paulo Henrique Condeixa de
Abstract excerpt
INTRODUCTION: Members of the Acinetobacter genus are key pathogens that cause healthcare-associated infections, and they tend to spread and develop new antibiotic resistance mechanisms. Oxacillinases are primarily responsible for resistance to carbapenem antibiotics. Higher rates of carbapenem hydrolysis might be ascribed to insertion sequences, such as the ISAba1 sequence, near bla OXA genes. The present study...
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