Article
A phase 2B study of MK-7009 (vaniprevir) in patients with genotype 1 HCV infection who have failed previous pegylated interferon and ribavirin treatment.
Journal of hepatology - 1 Jul 2013
Lawitz Eric, Rodriguez-Torres Maribel, Stoehr Albrecht, Gane Edward J, Serfaty Lawrence, Bhanja Sanhita, Barnard Richard J, An Di, Gress Jacqueline, Hwang Peggy, Mobashery Niloufar
Abstract excerpt
BACKGROUND & AIMS: MK-7009 (vaniprevir) is a non-covalent competitive inhibitor of the hepatitis C virus (HCV) NS3/4A protease. This report presents the primary analysis results (safety and sustained viral response) of a phase 2b study of MK-7009 given in combination with peginterferon (PegIFN) alfa2a 180 μg weekly and ribavirin (RBV) 1000-1200 mg/day, for 24-48 weeks to non-cirrhotic patients who have failed...
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