Article
Vaniprevir plus peginterferon alfa-2b and ribavirin in treatment-naive Japanese patients with hepatitis C virus genotype 1 infection: a randomized phase III study.
Journal of gastroenterology - 1 Apr 2016
Hayashi Norio, Nakamuta Makoto, Takehara Tetsuo, Kumada Hiromitsu, Takase Akiko, Howe Anita Yee Mei, Ludmerer Steven W, Mobashery Niloufar
Abstract excerpt
BACKGROUND: Vaniprevir is a potent macrocyclic hepatitis C virus (HCV) nonstructural protein 3/4A protease inhibitor. This phase III study evaluated the safety and efficacy of vaniprevir in combination with peginterferon alfa-2b and ribavirin (PR) for 24 weeks compared with PR alone for 48 weeks in treatment-naive Japanese patients with HCV genotype 1 infection. METHODS: Treatment-naive Japanese patients with HCV...
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