Article
Possible association between suicide committed under influence of ethanol and a variant in the AUTS2 gene.
PloS one - 1 Jan 2013
Chojnicka Izabela, Gajos Krzysztof, Strawa Katarzyna, Broda Grażyna, Fudalej Sylwia, Fudalej Marcin, Stawiński Piotr, Pawlak Aleksandra, Krajewski Paweł, Wojnar Marcin, Płoski Rafał
Abstract excerpt
BACKGROUND: rs6943555 in AUTS2 has been shown to modulate ethanol consumption. We hypothesized that rs6943555 might be associated with completed suicide. METHODS: We genotyped rs6943555 in 625 completed suicides and 3861 controls using real-time TaqMan Allelic Discrimination Assay. All individuals were Polish Caucasians. RESULTS: We detected an association between suicide and rs6943555 A allele (OR = 1.17,...
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