Article
Null genotypes of GSTM1 and GSTT1 contribute to hepatocellular carcinoma risk: evidence from an updated meta-analysis.
Journal of hepatology - 1 Sept 2010
Wang Bin, Huang Gang, Wang Dan, Li Aijun, Xu Zhipeng, Dong Ran, Zhang Deqiang, Zhou Weiping
Abstract excerpt
BACKGROUND & AIMS: Studies investigating the associations between glutathione S-transferase (GST) genetic polymorphisms and hepatocellular carcinoma (HCC) risk have reported controversial results. Thus, a meta-analysis was performed to clarify the effects of GSTM1 and GSTT1 polymorphisms on HCC risk. METHODS: We identified 132 relevant records through a literature search up to November 22, 2009, and 24 individual...
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