Article
Comprehensive SNP scan of DNA repair and DNA damage response genes reveal multiple susceptibility loci conferring risk to tobacco associated leukoplakia and oral cancer.
PloS one - 1 Jan 2013
Mondal Pinaki, Datta Sayantan, Maiti Guru Prasad, Baral Aradhita, Jha Ganga Nath, Panda Chinmay Kumar, Chowdhury Shantanu, Ghosh Saurabh, Roy Bidyut, Roychoudhury Susanta
Abstract excerpt
Polymorphic variants of DNA repair and damage response genes play major role in carcinogenesis. These variants are suspected as predisposition factors to Oral Squamous Cell Carcinoma (OSCC). For identification of susceptible variants affecting OSCC development in Indian population, the "maximally informative" method of SNP selection from HapMap data to non-HapMap populations was applied. Three hundred twenty-five...
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