TCF7L2 variation and proliferative diabetic retinopathy.

doi:10.2337/db12-1093

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

TCF7L2 variation and proliferative diabetic retinopathy.

Diabetes - 1 Jul 2013

Luo Jing, Zhao Ling, Chen Aaron Yun, Zhang Xiaohui, Zhu Jin, Zhao Jiagang, Ouyang Hong, Luo Hongrong, Song Yaojun, Lee Janet, Patel Sherrina H, Shaw Peter X, Sadda Srinivas, Zhuo Yehong, Rosenfeld Michael G, Zhang Kang

Abstract excerpt

Proliferative diabetic retinopathy (PDR) is the most severe vision-threatening complication of diabetes. For investigation of genetic association between TCF7L2 and PDR in Caucasian type 2 diabetes mellitus (T2DM) and its functional consequences, 383 T2DM patients with PDR (T2DM-PDR) and 756 T2DM patients without diabetic retinopathy (T2DM-no DR) were genotyped with rs7903146 in TCF7L2. We found that risk allele...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Diabetes Mellitus, Type 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetic Retinopathy

Share to Endoplasmic Reticulum Stress

Share to Gene Frequency

Share to Genetic Association Studies

Share to Retinal Neovascularization

Share to Transcription Factor 7-Like 2 Protein

Share to Vascular Endothelial Growth Factor A

Source

Open in PubMed Open full text

Identifiers

PMID: 23434931
DOI: 10.2337/db12-1093
PMCID: PMC3712060

Genes

VEGFA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

TCF7L2 variation and proliferative diabetic retinopathy.PMID 23434931Read ↗

Transcription factor 7-like 2 polymorphisms and diabetic retinopathy: a systematic review.Semantic proximity Read ↗

Association of transcription factor 7-like 2 (rs7903146) gene polymorphism with diabetic retinopathy.Semantic proximity Read ↗

Association between transcription factor 7-like 2 rs7903146 polymorphism and diabetic retinopathy in type 2 diabetes mellitus: A meta-analysis.Semantic proximity Read ↗

Haplotype-based association study of TCF7L2 gene variants with the development of diabetic retinopathy in an Iranian population.Semantic proximity Read ↗

Association between Transcription Factor 7-Like 2 C/T Polymorphism and Diabetic Retinopathy Risk: A Meta-Analysis.Semantic proximity Read ↗

Transcription factor 7-like 2 (TCF7L2) gene polymorphism and complication/comorbidity profile in type 2 diabetes patients.Semantic proximity Read ↗

Role of EPO and TCF7L2 Gene Polymorphism Contribution to the Occurrence of Diabetic Retinopathy.Semantic proximity Read ↗

Transcriptome analysis identified a novel 3-LncRNA regulatory network of transthyretin attenuating glucose induced hRECs dysfunction in diabetic retinopathySemantic proximity Read ↗

Differential transcriptional and posttranslational transcription factor 7-like regulation among nondiabetic individuals and type 2 diabetic patients.Semantic proximity Read ↗

An association between the sarcolemmal membrane-associated protein gene and microvascular endothelial diabetic retinopathy in patients with type 2 diabetes mellitus: A preliminary case control study.Semantic proximity Read ↗

TCF7L2 rs7903146 polymorphism and diabetic nephropathy association is not independent of type 2 diabetes--a study in a south Indian population and meta-analysis.Semantic proximity Read ↗

Correlation of the TCF7L2 (rs7903146) polymorphism with an enhanced risk of type 2 diabetes mellitus: a meta-analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.