Article
Selenistasis: epistatic effects of selenium on cardiovascular phenotype.
Nutrients - 31 Jan 2013
Joseph Jacob, Loscalzo Joseph
Abstract excerpt
Although selenium metabolism is intricately linked to cardiovascular biology and function, and deficiency of selenium is associated with cardiac pathology, utilization of selenium in the prevention and treatment of cardiovascular disease remains an elusive goal. From a reductionist standpoint, the major function of selenium in vivo is antioxidant defense via its incorporation as selenocysteine into enzyme...
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