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Article

Reduced expression of TRIF in chronic HBV infected Iranian patients.

Clinics and research in hepatology and gastroenterology - 1 Nov 2013

Ayoobi Fatemeh, Hassanshahi Gholamhossein, Zainodini Nahid, Khorramdelazad Hossein, Arababadi Mohammad Kazemi, Kennedy Derek

Abstract excerpt

BACKGROUND AND AIMS: TRIF is one of the main intracellular adaptor proteins required for TLR3 and 4 signaling. Abnormal gene expression of TRIF may lead to abrogated immune responses against viral infections including hepatitis B infection. The aim of this study was to identify the mRNA levels of TRIF in PBMCs isolated from chronic HBV (CHB) infected patients. MATERIAL AND METHODS: mRNA was isolated from 63 CHB...

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Share to Adaptor Proteins, Vesicular Transport
Share to Alanine Transaminase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Alkaline Phosphatase

Share to Aspartate Aminotransferases

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Share to Hepatitis B, Chronic

Share to Hepatitis B Surface Antigens

Share to Leukocytes, Mononuclear

Source

Identifiers

PMID: 23433963
DOI: 10.1016/j.clinre.2012.11.005

Genes

TLR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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