Article
BDNF gene polymorphism, cognition and symptom severity in a Brazilian population-based sample of first-episode psychosis subjects.
Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) - 1 Oct 2012
Martinho Eduardo, Michelon Leandro, Ayres Adriana M, Scazufca Marcia, Menezes Paulo R, Schaufelberger Maristela S, Murray Robin M, Rushe Teresa M, Vallada Homero, Busatto Filho Geraldo
Abstract excerpt
OBJECTIVE: To investigate the influence of brain-derived neurotrophic factor (BDNF) gene variations on cognitive performance and clinical symptomatology in first-episode psychosis (FEP). METHODS: We performed BDNF val66met variant genotyping, cognitive testing (verbal fluency and digit spans) and assessments of symptom severity (as assessed with the PANSS) in a population-based sample of FEP patients (77 with...
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