Wavelength dependence for UV-induced pyrimidine dimer formation in DNA of human peripheral blood lymphocytes.

doi:10.1016/0921-8777(90)90072-d

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Article

Wavelength dependence for UV-induced pyrimidine dimer formation in DNA of human peripheral blood lymphocytes.

Mutation research - 1 May 1990

Freeman S E, Ryan S L

Abstract excerpt

An action spectrum for the induction of pyrimidine dimers in human peripheral lymphocytes was determined between 254 and 405 nm. The presence of pyrimidine dimers was determined as UV-induced lesions that were sensitive to the dimer-specific endonuclease from Micrococcus luteus in conjunction wit...

Topics

Cell Survival
DNA
Dose-Response Relationship, Radiation
Electrophoresis, Agar Gel
Humans
Lymphocytes
Mutation
Pyrimidine Dimers
Ultraviolet Rays

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