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Article

Virus host protein interaction network analysis reveals that the HEV ORF3 protein may interrupt the blood coagulation process.

PloS one - 1 Jan 2013

Geng Yansheng, Yang Jun, Huang Weijin, Harrison Tim J, Zhou Yan, Wen Zhiheng, Wang Youchun

Abstract excerpt

Hepatitis E virus (HEV) is endemic worldwide and a major cause of acute liver disease in developing countries. However, the molecular mechanisms of liver pathology and clinical disease are not well understood for HEV infection. Open reading frame 3 (ORF3) of HEV encodes a small phosphoprotein, which is assumed to be involved in liver pathology and clinical disease. In this study, the interactions between the HEV...

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Identifiers

PMID: 23418552
DOI: 10.1371/journal.pone.0056320
PMCID: PMC3571956

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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