Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Influence of CFH, HTRA1 and ARMS2 haplotype polymorphisms in the development of age-related macular disease.

Archivos de la Sociedad Espanola de Oftalmologia - 1 Jan 2013

Cruz-González F, Lorenzo-Pérez R, Cañete-Campos C, Hernández-Galilea E, González-Sarmiento R

Abstract excerpt

OBJECTIVE: To demonstrate genetic influence on the onset of age-related macular disease (AMD), analyzing genotype distribution of haplotypes, including polymorphisms of genes with proved relationships with AMD risk (CFH, ARMS2, HTRA1) in patients with AMD and in healthy people. METHODS: We took 101 consecutive patients with an AMD diagnosis following Wisconsin international classification. For our control group,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Complement Factor H

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Haplotypes

Share to High-Temperature Requirement A Serine Peptidase 1

Share to Macular Degeneration

Share to Polymorphism, Genetic

Share to Proteins

Share to Serine Endopeptidases

Source

Identifiers

PMID: 23414945
DOI: 10.1016/j.oftal.2012.04.019

Genes

ARMS2
CFH
HTRA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Influence of CFH, HTRA1 and ARMS2 haplotype polymorphisms in the development of age-related macular disease.PMID 23414945Read ↗

CFH (rs1410996), HTRA1 (rs112000638) and ARMS2 (rs10490923) gene polymorphisms are associated with AMD risk in Spanish patients.Semantic proximity Read ↗

Association of single nucleotide polymorphisms in CFH, ARMS2 and HTRA1 genes with risk of age-related macular degeneration in Egyptian patients.Semantic proximity Read ↗

The presence of CFH, HTRA1, ARMS2, VEGF-A and VEGF-R and the appearance of age-related macular degeneration sub-types.Semantic proximity Read ↗

Association analysis of CFH and ARMS2 gene polymorphisms in a Brazilian cohort with age-related macular degeneration.Semantic proximity Read ↗

C-reactive protein and CFH, ARMS2/HTRA1 gene variants are independently associated with risk of macular degeneration.Semantic proximity Read ↗

Recombinant Haplotypes Narrow the ARMS2/HTRA1 Association Signal for Age-Related Macular DegenerationSemantic proximity Read ↗

Gene polymorphisms associated with an increased risk of exudative age-related macular degeneration in a Spanish population.Semantic proximity Read ↗

The interactions between ARMS2, CFH, VEGF-A and environmental factors on the risk of age-related macular degeneration.Semantic proximity Read ↗

The contribution of genetic factors to phenotype and progression of drusen in early age-related macular degeneration.Semantic proximity Read ↗

LOC387715/HTRA1 gene polymorphisms and susceptibility to age-related macular degeneration: A HuGE review and meta-analysis.Semantic proximity Read ↗

Association of specific genetic polymorphisms with age-related macular degeneration in a northern Chinese population.Semantic proximity Read ↗

Variations in five genes and the severity of age-related macular degeneration: results from the Muenster aging and retina study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.