Article
The association between the methionine/valine (M/V) polymorphism (rs1799990) in the PRNP gene and the risk of Alzheimer disease: an update by meta-analysis.
Journal of the neurological sciences - 15 Mar 2013
He Jie, Li Xiaoyan, Yang Jiqiao, Huang Jichong, Fu Xiaowei, Zhang Yonggang, Fan Hong
Abstract excerpt
BACKGROUND: The M/V polymorphism in the PRNP gene has been extensively examined for the association to the risk of Alzheimer disease (AD); however, results from different studies have been inconsistent. The aim of this study is to evaluate the association between the M/V polymorphism in the PRNP gene and the risk of AD. METHODS: A meta-analysis was carried out to analyze the association between the M/V...
Topics
- Alzheimer Disease
- Case-Control Studies
- Genetic Association Studies
- Genetic Predisposition to Disease
- Humans
- Methionine
- Polymorphism, Genetic
- Prion Proteins
- Prions
- Valine