Article
Effects of N-acetyl-L-cysteine on bleomycin induced oxidative stress in malignant testicular germ cell tumors.
Biochimie - 1 Dec 2012
Cort Aysegul, Ozdemir Evrim, Timur Mujgan, Ozben Tomris
Abstract excerpt
Testicular cancer is a very common cancer in males aged 15-44 years. Bleomycin is used in chemotherapy regimens in the treatment of patients having testicular germ-cell tumor. Bleomycin generates oxygen radicals, induces oxidative cleavage of DNA strand and induces apoptosis in cancer cells. Ther...
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