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Article

Circulating microRNAs as biomarkers for early detection of diffuse-type gastric cancer using a mouse model

5 Feb 2013

Abstract excerpt

BACKGROUND: Diffuse-type gastric cancer (DGC) exhibits rapid disease progression and a poor prognosis. There are no effective serum biomarkers for early detection of DGC. We have established an E-cadherin/p53 double conditional knockout (DCKO) mouse line that recapitulates human DGC morphologically and molecularly. In this study we tried to identify circulating microRNAs (miRNAs) as non-invasive biomarkers for...

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PMID: 23385731
DOI: 10.1038/bjc.2013.30

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