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Article

A new strategy to produce a defensin: stable production of mutated NP-1 in nitrate reductase-deficient Chlorella ellipsoidea.

PloS one - 1 Jan 2013

Bai Li-Li, Yin Wei-Bo, Chen Yu-Hong, Niu Li-Li, Sun Yong-Ru, Zhao Shi-Min, Yang Fu-Quan, Wang Richard R-C, Wu Qing, Zhang Xiang-Qi, Hu Zan-Min

Abstract excerpt

Defensins are small cationic peptides that could be used as the potential substitute for antibiotics. However, there is no efficient method for producing defensins. In this study, we developed a new strategy to produce defensin in nitrate reductase (NR)-deficient C. ellipsoidea (nrm-4). We constructed a plant expression vector carrying mutated NP-1 gene (mNP-1), a mature α-defensin NP-1 gene from rabbit with an...

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Identifiers

PMID: 23383016
DOI: 10.1371/journal.pone.0054966
PMCID: PMC3557228

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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