Article
Coalescent inference for infectious disease: meta-analysis of hepatitis C.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 19 Mar 2013
Dearlove Bethany, Wilson Daniel J
Abstract excerpt
Genetic analysis of pathogen genomes is a powerful approach to investigating the population dynamics and epidemic history of infectious diseases. However, the theoretical underpinnings of the most widely used, coalescent methods have been questioned, casting doubt on their interpretation. The aim of this study is to develop robust population genetic inference for compartmental models in epidemiology. Using a...
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