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Article

Reevaluation of fatty acid receptor 1 as a drug target for the stimulation of insulin secretion in humans.

Diabetes - 1 Jun 2013

Wagner Robert, Kaiser Gabriele, Gerst Felicia, Christiansen Elisabeth, Due-Hansen Maria E, Grundmann Manuel, Machicao Fausto, Peter Andreas, Kostenis Evi, Ulven Trond, Fritsche Andreas, Häring Hans-Ulrich, Ullrich Susanne

Abstract excerpt

The role of free fatty acid receptor 1 (FFAR1/GPR40) in glucose homeostasis is still incompletely understood. Small receptor agonists stimulating insulin secretion are undergoing investigation for the treatment of type 2 diabetes. Surprisingly, genome-wide association studies did not discover diabetes risk variants in FFAR1. We reevaluated the role of FFAR1 in insulin secretion using a specific agonist,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23378609
DOI: 10.2337/db12-1249
PMCID: PMC3661642

Genes

FFAR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

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Reevaluation of fatty acid receptor 1 as a drug target for the stimulation of insulin secretion in humans.PMID 23378609Read ↗

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