Article
Cystic fibrosis transmembrane conductance regulator (ABCC7) structure.
Cold Spring Harbor perspectives in medicine - 1 Feb 2013
Hunt John F, Wang Chi, Ford Robert C
Abstract excerpt
Structural studies of the cystic fibrosis transmembrane conductance regulator (CFTR) are reviewed. Like many membrane proteins, full-length CFTR has proven to be difficult to express and purify, hence much of the structural data available is for the more tractable, independently expressed soluble domains. Therefore, this chapter covers structural data for individual CFTR domains in addition to the sparser data...
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